Daunorubicin therapy in advanced neuroblastoma
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I-131 MIBG Therapy for Advanced Stage III & IV Neuroblastoma
Radio-labelled MIBG therapy has been tried in the treatment of advanced stage III and IV neuroblastoma in an attempt to improve patients outcome. The use of radiolabelled MIBG to treat neuroblastoma has arisen from the high sensitivity and specificity of in vivo MIBG imaging for detection of primary and metastatic tumours. Although, clinical trials have been performed to determine the role of M...
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Retinoids are analogues of vitamin A, with documented activity against various malignant cell types. Neuroblastoma is a childhood tumour of the sympathetic nervous system that shows a complex clinical and biological heterogeneity, often with poor outcome despite intensive multimodal therapy. The aim of the thesis was to investigate effects of retinoid treatment in vitro on human neuroblastoma c...
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INTRODUCTION Neuroblastoma, a neoplasm of the sympathetic nervous system, is the second most extracranial malignant solid tumor of childhood. Many therapeutic strategies has evolved over the last 20 years, based upon work by international cooperative groups and smaller cohort studies. Novel therapies to improve initial disease response and treatment of minimal residual disease are required to i...
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ژورنال
عنوان ژورنال: Cancer
سال: 1971
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197104)27:4<831::aid-cncr2820270412>3.0.co;2-z